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	<title>Comments on: THE EVER PRESCIENT LEDERBERG</title>
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	<link>http://hybridvigor.org/2008/02/11/the-ever-prescient-lederberg/</link>
	<description>Improving decisions and outcomes through collaboration and deliberation</description>
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		<title>By: Denise Caruso</title>
		<link>http://hybridvigor.org/2008/02/11/the-ever-prescient-lederberg/comment-page-1/#comment-9896</link>
		<dc:creator>Denise Caruso</dc:creator>
		<pubDate>Tue, 12 Feb 2008 20:57:31 +0000</pubDate>
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		<description>Definitely agree that the prognosis is good for the communications aspects -- I&#039;m especially interested in how some of the big grid computing projects will fare over the years. I wrote a kind of fun piece for NYT about collaborative software some years ago: http://query.nytimes.com/gst/fullpage.html?res=9A04E0DE1F30F936A35752C1A9679C8B63&amp;scp=21&amp;sq=%22denise+caruso%22&amp;st=nyt 

I&#039;d love to know what areas specifically that computers are undervalued in scientific pursuit. I am sure that&#039;s true in many fields, but it would be interesting to see where from your perspective. (Also, what is your perspective? Are you a working scientist? Just curious.) 

In biotech, interestingly, there are some important instances where computers -- or at the very least, automation -- can tip to the &quot;overvalued&quot; side. The most obvious example:  gene-disease links. 

We&#039;ve all heard about &quot;the gene&quot; responsible for producing various diseases in individuals -- diabetes, Alzheimerâ€™s, obesity, schizophrenia, depression, etc. But in early 2005, a study reported that as many as 95 percent of these gene-disease links don&#039;t actually exist.

The main reason cited is the speed and efficiency with which computers can sequence and analyze genes. Reading gene sequences can take about a day now instead of several months, but because the sequences are analyzed by software without a human reality check, some of them get linked randomly to a disease in a statistically significant way. 

Everybody is eager to publish a new link, but as the study authors said, they don&#039;t usually submit the &quot;Ooops! Our bad&quot; stories, and journals don&#039;t often print retractions. And so a reductionist view of biology persists. 

Just a warning flag about the reliability/fallibility continuum of technology ...</description>
		<content:encoded><![CDATA[<p>Definitely agree that the prognosis is good for the communications aspects &#8212; I&#8217;m especially interested in how some of the big grid computing projects will fare over the years. I wrote a kind of fun piece for NYT about collaborative software some years ago: <a href="http://query.nytimes.com/gst/fullpage.html?res=9A04E0DE1F30F936A35752C1A9679C8B63&#038;scp=21&#038;sq=%22denise+caruso%22&#038;st=nyt" rel="nofollow">http://query.nytimes.com/gst/fullpage.html?res=9A04E0DE1F30F936A35752C1A9679C8B63&#038;scp=21&#038;sq=%22denise+caruso%22&#038;st=nyt</a> </p>
<p>I&#8217;d love to know what areas specifically that computers are undervalued in scientific pursuit. I am sure that&#8217;s true in many fields, but it would be interesting to see where from your perspective. (Also, what is your perspective? Are you a working scientist? Just curious.) </p>
<p>In biotech, interestingly, there are some important instances where computers &#8212; or at the very least, automation &#8212; can tip to the &#8220;overvalued&#8221; side. The most obvious example:  gene-disease links. </p>
<p>We&#8217;ve all heard about &#8220;the gene&#8221; responsible for producing various diseases in individuals &#8212; diabetes, Alzheimerâ€™s, obesity, schizophrenia, depression, etc. But in early 2005, a study reported that as many as 95 percent of these gene-disease links don&#8217;t actually exist.</p>
<p>The main reason cited is the speed and efficiency with which computers can sequence and analyze genes. Reading gene sequences can take about a day now instead of several months, but because the sequences are analyzed by software without a human reality check, some of them get linked randomly to a disease in a statistically significant way. </p>
<p>Everybody is eager to publish a new link, but as the study authors said, they don&#8217;t usually submit the &#8220;Ooops! Our bad&#8221; stories, and journals don&#8217;t often print retractions. And so a reductionist view of biology persists. </p>
<p>Just a warning flag about the reliability/fallibility continuum of technology &#8230;</p>
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		<title>By: Deepak</title>
		<link>http://hybridvigor.org/2008/02/11/the-ever-prescient-lederberg/comment-page-1/#comment-9888</link>
		<dc:creator>Deepak</dc:creator>
		<pubDate>Tue, 12 Feb 2008 17:18:59 +0000</pubDate>
		<guid isPermaLink="false">http://hybridvigor.net/2008/02/11/the-ever-prescient-lederberg/#comment-9888</guid>
		<description>Wholeheartedly agree.  Of course, even the use of computers for scientific pursuit is pitifully undervalued, although not as much as it used to be,

The good news.  A lot has happened in the past couple of years, so the prognosis for the communication aspect of computing is a good one.</description>
		<content:encoded><![CDATA[<p>Wholeheartedly agree.  Of course, even the use of computers for scientific pursuit is pitifully undervalued, although not as much as it used to be,</p>
<p>The good news.  A lot has happened in the past couple of years, so the prognosis for the communication aspect of computing is a good one.</p>
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